Down syndrome and the eye: ocular characteristics and ocular assessment

The trisomy of chromosome 21, the smallest autosome, is associated with significant systemic manifestations in addition to intellectual disability. The triplication of this chromosome, known as Down syndrome (DS) is also associated with several manifestations in the eye and ocular adnexae. People with DS have a variety of ophthalmic conditions, some of which require intervention. The variable systemic and ophthalmic presentations in DS can make the delivery of eye care challenging. We highlight common ophthalmic presentations in people with DS, as well as the practical implications of delivering eye examinations for this complex needs population.

Source: Survey of Ophthalmology - April 1, 2022 Category: Opthalmology Authors: Joyce John Mathan, Samantha Kaye Simkin, Akilesh Gokul, Charles Ninian John McGhee Source Type: research