Reactive oxygen species - responsive RNA interference

Chem. Commun., 2022, Accepted Manuscript DOI: 10.1039/D2CC00651K, CommunicationJennifer R ühle, Insa Klemt, Tatiana O. Abakumova, Olga Sergeeva, Polina Vetosheva, Timofei S. Zatsepin, Andriy Mokhir Due to oxidative instability, arylboronic acids are not compatible with solid phase synthesis of nucleic acids. We solved this problem and, based on these findings, developed siRNA prodrugs, activated in... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chem. Commun. latest articles - March 8, 2022 Category: Chemistry Authors: Jennifer R ühle Source Type: research