Mechanism of darunavir binding to monomeric HIV-1 protease: A step forward in rational design of dimerization inhibitors

Phys. Chem. Chem. Phys., 2022, Accepted Manuscript DOI: 10.1039/D2CP00024E, PaperMohd Ahsan, Chinmai Pindi, Sanjib Senapati HIV protease (HIVPR) is a key target in AIDS therapeutics. All ten FDA-approved drugs that compete with the substrates in binding to this dimeric enzyme ’s active site become ineffective due... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Phys. Chem. Chem. Phys. latest articles - February 28, 2022 Category: Chemistry Authors: Mohd Ahsan Source Type: research