Impact of UCP2 depletion on heat stroke-induced mitochondrial function in human umbilical vein endothelial cells

CONCLUSION: Our results indicate that UCP2 protects against HS-induced vascular endothelial damage and that it enhances mitochondrial function. These findings reveal that UCP2 can be a potential contributor to mechanism-based therapeutic strategies for HS.PMID:35129048 | DOI:10.1080/02656736.2022.2032846

Source: International Journal of Hyperthermia - February 7, 2022 Category: Internal Medicine Authors: Wei Huang Liangfeng Mao Weidang Xie Sumin Cai Qiaobing Huang Yanan Liu Zhongqing Chen Source Type: research