Non-Invasive Fetal K Status Prediction: 7 Years of Experience

Conclusion: We have developed an NGS-based method for the non-invasive prediction of fetal K status. This approach requires special considerations in terms of primer design, stringent preanalytical sample handling, and careful analytical procedures. We analyzed samples starting at GA 10 weeks and demonstrated the correct prediction of fetal K status. This assay enables timely clinical intervention in pregnancies at risk of hemolytic disease of the fetus and newborn caused by maternal anti-K IgG antibodies.Transfus Med Hemother

Source: Transfusion Medicine and Hemotherapy - January 31, 2022 Category: Hematology Source Type: research