Gut symbionts dial up RA to prime host defense

Cell Host Microbe. 2021 Dec 8;29(12):1727-1729. doi: 10.1016/j.chom.2021.11.011.ABSTRACTIn this issue of Cell Host & Microbe, Woo et al. (2021) show that retinoic acid generated by symbiotic segmented filamentous bacteria in the intestine primes host intestinal epithelial defense and mediates early innate immune protection against Citrobacter rodentium infection.PMID:34883060 | DOI:10.1016/j.chom.2021.11.011

Source: Cell Host and Microbe - December 9, 2021 Category: Microbiology Authors: Jitender Yadav Nayanan Nathan Dana J Philpott Source Type: research