Janus kinase inhibition in induction treatment of anti ‐MDA5 juvenile dermatomyositis‐associated rapidly progressive interstitial lung disease

AbstractTofacitinib has an important role in pediatric rapidly progressive interstitial lung disease (ILD) associated with juvenile dermatomyositis (JDM), an otherwise potentially fatal condition. It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and interleukin-18 are useful markers for tracking activity and response of JDM-associated ILD.

Source: International Journal of Rheumatic Diseases - December 9, 2021 Category: Rheumatology Authors: Poh Lin Pauline Chan Ng, Archana Mopur, Daniel Yam Thiam Goh, Mahesh  Babu Ramamurthy, Michael Teik Chung Lim, Lee Kean Lim, Pei Ling Ooi, Elizabeth Youning Ang Tags: APLAR GRAND ROUND CASE Source Type: research