Phenotypic Changes of PD-1 and GITR in T Cells Are Associated With Hepatitis B Surface Antigen Seroclearance

Conclusions: The reduced expression of PD-1 and GITR might attenuate the immunosuppressive capability of Tregs. Decreased expression on CD4+ T cells might represent an enhanced antiviral function, playing a role in initiating the “functional cure” of chronic HBV infection.
Source: Journal of Clinical Gastroenterology - Category: Gastroenterology Tags: Online Articles: Original Articles Source Type: research