Dementia: The 'difficulty' in the middle of the night that can signal onset of dementia

AS MORE and more focus is brought onto dementia and more people begin to discuss it day to day, the more awareness there will be of it's symptoms and what to look out for. According to Dementia UK, there is one symptom that can happen in the middle of the night that might signal that a loved one has the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Condition:   Dementia Caregivers Intervention:   Device: Cereset Research Sponsors:   Wake Forest University Health Sciences;   Memory Counseling Program general fund;   Heidi Munger-Clary, MD;   Hossam Shaltout, PhD;   Sean Simpson, PhD;   Christina Hugenschmidt, PhD;   Mia Yang, MD Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
WEDNESDAY, Jan. 26, 2022 (American Heart Association News) -- Brain diseases, including Alzheimer's disease and other forms of dementia, are closely connected to heart health. They are affected by everyday actions and rank among the nation's leading...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
A ribosome performs the translation portion of the process of gene expression, assembling protein molecules from amino acid building blocks according to the blueprint provided by messenger RNA molecules. The more efficiently a ribosome operates, the better a cell functions. Like all cellular components, the ribosome is negatively impacted by age, leading to a greater rate of errors in protein manufacture. The causes of this decline are not well understood, at least when it comes to drawing a clear line of causation back to the root causes of aging. It is perhaps noteworthy that long-lived naked mole rats have evolved unusu...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Researchers here discuss analysis of images of the retina as a way to produce biomarkers of aging. Older people with a predicted age that is higher than their chronological age, based on retinal imagery, exhibit a higher mortality rate. The growing diversity of clocks estimating biological age illustrate that just about every sizable set of biological data can mined to produce algorithmic combinations of data that correlate with mortality and incidence of age-related disease. Producing these clocks is the easy part of the task. It will be harder to calibrate and understand the clocks well enough to use them to assess the e...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
On a cold October morning in Lander, Wyo., Liz Lightner makes a few mental notes as she sits by a stranger’s bedside. The man is 79, has lung cancer and is in a deep-sleep coma. He’s wearing a blue scuba-diving shirt that’s worn out and looks as if it’s been loved, washed and rewashed for many years. Besides the company of his cat, the man is alone and moments from dying. Using only words, Lightner, 49, carries him away from a home that he can’t physically leave anymore and guides him under the sea, where she knows he used to be happy. She leans her head against his chest and tells him they&rs...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 nationpod Source Type: news
Conclusion: Older adults with higher burden of CMVD, driven especially by diabetes, are likely to increase the risk of prevalent and incident MCI and dementia.Gerontology
Source: Gerontology - Category: Geriatrics Source Type: research
The actor has been diagnosed with dementia but campaigners believe the legal arrangement is not in her best interestIn the wake of Britney Spears ’ emancipation from her long-term conservatorship, some of Britney’s fans have turned their attention to the Star Trek actor Nichelle Nichols. Last week a dozen protesters, a mixture of Free Britney activists and fans of Nichols, demonstrated outside the Stanley Mosk courthouse in Los Angeles, c hanting “Free Nichelle!”Nichols has been living under a conservatorship since 2018. Her son Kyle Johnson successfully petitioned to be his mother ’s conserva...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Ageing Star Trek Law (US) US television Source Type: news
The intracellular misfolding and accumulation of alpha-synuclein into structures collectively called Lewy pathology (LP) is a central phenomenon for the pathogenesis of synucleinopathies, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Understanding the molecular architecture of LP is crucial for understanding synucleinopathy disease origins and progression. Here we...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Neuroscience Biological Sciences Source Type: research
AbstractPrimary palliative care is a fundamental aspect of high-quality care for patients with a serious illness such as dementia. The clinician caring for a patient and family suffering with dementia can provide primary palliative care in numerous ways. Perhaps the most important aspects are high  quality communication while sharing a diagnosis, counseling the patient through progression of illness and prognostication, and referral to hospice when appropriate. COVID-19 presents additional risks of intensive care requirement and mortality which we must help patients and families navigate. Th roughout all of these disc...
Source: Neurotherapeutics - Category: Neurology Source Type: research
AbstractRhoGDI α is an inhibitor of RhoGDP dissociation that involves in Aβ metabolism and NFTs production in Alzheimer's disease (AD) by regulating of RhoGTP enzyme activity. Our previous research revealed that RhoGDIα, as the target of Polygala saponin (Sen), might alleviate apoptosis of the nerve cells cause d by hypoxia/reoxygenation (H/R). To further clarify the role of RhoGDIα in the generation of NFTs, we explored the relationship between RhoGDIα and Tau. We found out that RhoGDIα and Tau can bind with each other and interact by using coimmunoprecipitation (Co-IP) and GST pulldown ...
Source: Journal of NeuroImmune Pharmacology - Category: Drugs & Pharmacology Source Type: research
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