Models of Care for Postacute COVID-19 Clinics: Experiences and a Practical Framework for Outpatient Physiatry Settings

We present five models of care in varying degrees of development and compare processes and adaptations to address the unique needs of each center and their unique patient populations. Forging a path to recovery will necessitate a multidisciplinary team with physiatry involvement to meet the distinctive needs of patients with postacute sequelae of SARS-CoV-2. Furthermore, it is imperative that there be equitable access to this care and commitment from healthcare institutions to provide resources for these programs.
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: SPECIAL SECTION on COVID-19 and PM&R Source Type: research

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Conclusions: In this study, postoperative SARS-CoV-2 infection was similar for individuals undergoing corneal transplantation or cataract surgery. Further research is required to evaluate the transmission of SARS-CoV-2 through corneal tissue.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Conclusions: The overall prevalence of SARS-CoV-2 was 1% (2% for conjunctival and 0% for corneal samples, P value = 0.5) in the donors who were found suitable for cornea recovery and transplantation. The findings of exceptionally low positive rates in our samples validate the criticality of history-based donor screening and do not support the necessity of postmortem PCR testing as a criterion for procurement and subsequent use for corneal transplantation.
Source: Cornea - Category: Opthalmology Tags: Basic Investigation Source Type: research
Conclusions: The novel SARS-CoV-2 vaccine upregulates the immune system to produce an adaptive immune response. The SARS-CoV-2 vaccine may potentially be associated with increased risk of rejection in those with ocular surface transplants.
Source: Cornea - Category: Opthalmology Tags: Case Report Source Type: research
Conclusions: To the best of our knowledge, this case of full-thickness graft rejection after the Moderna SARS-CoV-2 mRNA vaccination is the first to be reported worldwide. The temporal relationship between vaccination and subsequent rejection is highly suggestive of causation due to the short interval (3 days) between vaccination and rejection and the lack of other inciting factors in an otherwise healthy graft. Patients with corneal transplants who plan to take the COVID-19 vaccinations should be counseled on symptoms and closely monitored, and an individualized plan should be made in discussion with the ophthalmologist.
Source: Cornea - Category: Opthalmology Tags: Case Report Source Type: research
Although there are many hypotheses for the age-related difference in the severity of COVID-19, differences in innate, adaptive and heterologous immunity, together with differences in endothelial and clotting function, are the most likely mechanisms underlying the marked age gradient. Children have a faster and stronger innate immune response to SARS-CoV-2, especially in the nasal mucosa, which rapidly controls the virus. In contrast, adults can have an overactive, dysregulated and less effective innate response that leads to uncontrolled pro-inflammatory cytokine production and tissue injury. More recent exposure to other ...
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Review Articles Source Type: research
In October 2020, researchers discovered that the SARS-CoV-2 nonstructural protein 5 (NSP5) suppresses innate immunity. This has key implications for Covid-19 drug development that have yet to be fully explored.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Tags: Healthcare /healthcare Innovation /innovation Coronavirus business pharma & Source Type: news
This report describes COVID-19 cases and hospitalizations by vaccination status and previous COVID-19 diagnosis before and after the Delta variant became predominant.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Coronavirus [CoV] Immune system MMWR Morbidity & Mortality Weekly Report SARS (Severe acute respiratory syndrome) Vaccination Vaccines COVID-19 Source Type: news
As with any other ineradicable disease, prevention and treatment can be integrated into societyDelaying and preventing infection as much as possible through this pandemic was a worthwhile strategy. In early 2020, there were few treatments, limited testing and no vaccines. The costs of those lockdowns were big, but the effort to buy time paid off. In that time, science has transformed Covid from a deadly virus to a much less serious, nasty disease – one that is manageable at home, for the vast majority of those vaccinated. It has, largely, defanged it.But even as we have had success treating and preventing serious inf...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus Infectious diseases Health Medical research Microbiology Science UK news Vaccines and immunisation Source Type: news
Condition:   Covid19 Interventions:   Device: Face mask;   Behavioral: Face mask awareness;   Behavioral: Face mask promotion through community values or individual information Sponsors:   Yale University;   Stanford University;   University of California, Berkeley;   Innovations for Poverty Action;   North South University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Multiple Sclerosis (MS) Intervention:   Sponsor:   Biogen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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