First trimester anticoagulant exposure and adverse pregnancy outcomes in women with preconception venous thromboembolism: a nationwide cohort study

Venous thromboembolism, which refers to deep venous thrombosis plus pulmonary embolism, is a concern in women of childbearing age. Pregnancy is associated with a hypercoagulable state, such that pregnant women carry a 4- to 5-fold higher risk of venous thromboembolism compared to the general female population of reproductive age1. Venous thromboembolism incidence during pregnancy ranges from 0.6-2.0 events per 1000 deliveries1,2 with higher incidence in patients at high baseline risk such as thrombophilia or previous venous thromboembolism.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Research Study Source Type: research