Physiologic Changes during Neonatal Transition and the Influence of Respiratory Support

Very preterm infants have difficulties establishing effective breathing at birth because their lungs are structurally immature, surfactant-deficient, and not supported by a stiff chest wall.1 Indeed, 10% of newborn infants require respiratory support at birth, which is increasing with decreasing gestational age.2 The International Liaison Committee on Resuscitation recommends to provide positive pressure ventilation (PPV) for newborns who are apneic, bradycardic, or demonstrate inadequate respiratory effort immediately after birth.

Source: Clinics in Perinatology - November 11, 2021 Category: Perinatology & Neonatology Authors: Marlies Bruckner, Georg M. Schm ölzer Source Type: research