Cost-Utility Analysis of Discontinuing Antidepressants in England Primary Care Patients Compared with Long-Term Maintenance: The ANTLER Study

ConclusionsDiscontinuation of antidepressants was unlikely to be cost effective compared with maintenance for currently well patients on long-term antidepressants. However, this analysis provides no information on the wider impact of antidepressants. Our findings provide information on the potential impact of discontinuing long-term maintenance antidepressants and facilitate improving guidance  for shared patient–clinician decision making.Trial RegistrationEudraCT number 2015-004210-26; ISRCTN number ISRCTN15969819.
Source: Applied Health Economics and Health Policy - Category: Health Management Source Type: research