Mechanism of high expression of high mobility group protein 1 in a rat model of knee osteoarthritis

CONCLUSION: In the pathological process of KOA, NLRPs inflammasome-mediated FLS pyroptosis causes massive release of HMGB1, which is associated with the activation of the downstream molecule caspase-1.PMID:34549703 | DOI:10.12122/j.issn.1673-4254.2021.08.03
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Source Type: research