Africa: UN Honours Henrietta Lacks, Whose Cells Transformed Medical Research Worldwide
[UN News] For the past seven decades, the cells of Henrietta Lacks, a Black American woman who died of cervical cancer, have saved countless lives, and made numerous scientific breakthroughs possible, such as the human papillomavirus and polio vaccines, drugs for HIV treatment, together with cancer and COVID-19 research.
Prevalences, nuances of presentation, and likely clinical course of myocarditis after use of some vaccines against SARS-CoV-2 are in sharper view after additions to the literature this week.Medscape Medical News
Immune checkpoint inhibitors can be effective in patients with non-small cell lung cancer and mild interstitial lung disease, but with a greater risk.Medscape Medical News
AbstractPurposeGenetic variants may influence the pharmacokinetics and pharmacodynamics (PKPD) of cyclophosphamide (CY). CY plays a critical role in conditioning chemotherapy for hematopoietic cell transplantation (HCT), but its use is limited by toxicity. We explored the effect of genetic variants, potentially affecting PKPD of CY, and outcomes after HCT.MethodsThis observational pharmacogenomic study included 85 adults with hematologic malignancies who received reduced intensity conditioning with CY, fludarabine, and total body irradiation. We collected recipient DNA prior to HCT and evaluated 97 candidate variants in 66...
Oncogene, Published online: 27 January 2022; doi:10.1038/s41388-021-02158-wSELENOF is a new tumor suppressor in breast cancer
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Mariana Rodriguez-Hakim, Linard R äz, Jan Vermant Some contagious diseases, such as COVID-19, spread through the transmission of aerosols and droplets. Aerosol and droplet formation occurs inside and outside of the respiratory tract, the latter being observed... The content of this RSS Feed (c) The Royal Society of Chemistry
Dalton Trans., 2022, Accepted Manuscript DOI: 10.1039/D1DT04315C, PaperXiang Wang, Kang Song, Yong Deng, Jie Liu, Qin Peng, Xiao Lao, Jiayu Xu, Dong Wang, Turong Shi, Yuhao Li, Dan Deng, Yuqing Miao Photodynamic therapy (PDT) is an effective non-invasive treatment for tumors. The structure of the photosensitizer has an important influence on the light utilization and the efficiency of singlet-oxygen generation. In... The content of this RSS Feed (c) The Royal Society of Chemistry
Chem. Commun., 2022, Advance Article DOI: 10.1039/D1CC06330H, CommunicationXiao-Jie Dong, Wen-Yan Li, Qun Guan, Yan-An Li, Yu-Bin Dong A COF-based multifunctional nanomedicine CuS@COF-BDP, which can be used as a PTT/PDT bimodal therapeutic agent to inhibit cancer cell proliferation under visible- and NIR-II-light irradiation, is reported. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Abbott Laboratories has distributed more than 1.4 billion Covid-19 tests globally since the start of the pandemic, including around 300 million in the fourth quarter of 2021. Its global Covid-19 testing-related sales were $2.3 billion in the fourth quarter and $7.7 billion for the full year in 2021.
A deep molecular dive into COVID-19 patients found that the presence of autoantibodies in peripheral blood at initial diagnosis was the chief of four risk factors predicting if a patient would experience long COVID.Medscape Medical News
Now that the U.S. Food and Drug Administration has authorized Pfizer-BioNTech’s vaccine for kids aged 5 to 11, the Biden Administration has signaled that it will rely on a “trusted messenger” to get information to parents and provide access to vaccines once they’re approved by the Centers for Disease Control and Prevention: schools. As part of the plan to deliver COVID-19 vaccines to the youngest population yet, schools will again take on a role they’ve assumed during health crises throughout American history: promoting vaccination to keep kids and communities safe from infectious disease. &ld...