Estimation of pancreatic fibrosis and prediction of postoperative pancreatic fistula using extracellular volume fraction in multiphasic contrast-enhanced CT

ConclusionsThe ECV fraction can offer quantitative information for assessing pancreatic fibrosis and POPF after pancreaticojejunal anastomosis.Key Points•There was a moderate positive correlation of the extracellular volume (ECV) fraction of the pancreas in contrast-enhanced CT with the histologic grade of pancreatic fibrosis (r = 0.476; p <  0.001).•The ECV fraction was higher in advanced fibrosis (F2 ‒F3) than in no/mild fibrosis (F0‒F1) (p <  0.001), with an AUC of 0.837 for detecting advanced fibrosis.•The ECV fraction was an independent risk factor for predicting subclinical (odds ratio, 0.81) and clinical (odds ratio, 0.80) postoperative pancreatic fistula.

Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research