Undifferentiated Small Round Cell Sarcomas of Bone

This article highlights current trends in their classification based on morphology, immunohistochemistry, and advanced molecular techniques. As next-generation sequencing becomes commonplace in diagnostic laboratories pathologists can expect to differentiate these tumors with increasing confidence, and actively contribute to related discoveries. Ultimately, when synthesized with rigorous clinical outcome data and other investigative techniques, a more robust landscape for the molecular diagnosis and classification of undifferentiated small round cell sarcomas is expected to emerge in the future.

Source: Surgical Pathology Clinics - October 7, 2021 Category: Pathology Authors: Brendan C. Dickson Source Type: research