Lyme Disease: A Probably Underdiagnosed Cause of Mono-Arthritis
Teaching point: Meticulous anamnesis and a high index of suspicion is needed for the diagnosis of Lyme arthritis. Published on 2021-09-21 11:30:32
Conclusions: Operative management of pediatric patients with Lyme arthritis is associated with increased resource utilization and costs while being similarly efficacious to nonoperative management. As the US Lyme epidemic expands, improved diagnosis and management of acute undifferentiated arthritis may prevent unneeded operative intervention. Level of Evidence: Level III—retrospective cohort study.
CONCLUSIONS: The presence of IgG antibodies against a number of Borreliella antigens and the differences in the IL-2 and MMP2 levels in seropositive or seronegative individuals and symptomatic LB patients, may indicate differences in the intensity of the immune response to the infection and, consequently, may induce development of clinical manifestations of the disease in seropositive and seronegative individuals.PMID:34558260 | DOI:10.26444/aaem/124088