Vaccine-induced immune thrombotic thrombocytopenia presenting with normal platelet count

We report on three patients who presented to our institute with this syndrome. Noteworthy in our presentations are two patients who presented for medical assessment of thrombotic symptoms with a normal platelet count, one preceding and one following a period of thrombocytopenia. Prompt diagnosis of VITT is critical to prevent rapid patient decline. We provide herein a new diagnostic algorithm that we believe will help optimally capture case presentations of VITT. These cases broaden and refine our understanding of the disease process and highlight to practitioners that VITT cannot be adequately ruled out by thrombocytopenia alone.PMID:34532632 | PMC:PMC8440941 | DOI:10.1002/rth2.12596
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Source Type: research