Next Generation Sequencing (NGS) to Determine Microbiome of Herniated Intervertebral Disc

Low back pain is a very common complaint and up to 84% of the adult population will suffer from it at some point in their lives.[1] Degenerative disc disease has a strong relationship to chronic low back pain although it is mostly asymptomatic. Disc degeneration involves alterations to its microstructure, inability of the disc annulus and nucleous to share load, and loss of disc height.[2] This could lead to conditions such as disc herniation, ligaments and facet joints hypertrophy and nerve compression.

Source: The Spine Journal - September 18, 2021 Category: Orthopaedics Authors: Nelson Astur, Brenno Ferreira Bento Maciel, Andre Mario Doi, Marines Dalla Valle Martino, Marcela Souza Basqueira, Marcelo Wajchenberg, Mario Lenza, Delio Eulalio Martins Source Type: research