Pulmonary Innate Lymphoid Cell Responses during Rhinovirus-induced Asthma Exacerbations < em > In Vivo < /em > : A Clinical Trial

Conclusions An ILC2-predominant inflammatory profile in asthma was associated with increased severity and duration of rhinovirus infection compared with healthy subjects, supporting the potential role of ILC2s in the pathogenesis of virus-induced asthma exacerbations. Clinical trial registration available at www.clinicaltrials.gov, ID: NCT01773590.PMID:34469272 | DOI:10.1164/rccm.202010-3754OC

Source: Am J Respir Crit Car... - September 1, 2021 Category: Intensive Care Authors: Jaideep Dhariwal Aoife Cameron Ernie Wong Malte Paulsen Belen Trujillo-Torralbo Ajerico Del Rosario Eteri Bakhsoliani Tatiana Kebadze Mark Almond Hugo Farne Leila Gogsadze Julia Aniscenko Batika Rana Trevor T Hansel David J Jackson Onn Min Kon Michael R E Source Type: research