Report on Lung Cancer from the ASCO 2021 virtual congress, June 4th –8th

Source: Memo - Magazine of European Medical Oncology - Category: Cancer & Oncology Source Type: research

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In this study, we aimed to explore the effect of sex differences on immune cell infiltration in lung tumor microenvironment (TME), and tried to clarify the reasons for the different clinical characteristics of male and female LUAD patients, by conducting a comp arative analysis of the TME.MethodsUsing ESTIMATE algorithm, we calculated immune and stromal scores of tumor samples downloaded from TCGA database according to immune  or stromal components in TME. GO and KEGG enrichment analysis were conducted to reveal biological processes of these intersecting genes of high- and low-score groups. Cox regression analysis and...
Source: Biology of Sex Differences - Category: Biology Source Type: research
Cancer-associated venous thromboembolism (VTE) is common in patients with primary lung cancer. It has been understudied which authoritative risk assessment score of cancer-associated VTE is optimal for the ass...
Source: Thrombosis Journal - Category: Hematology Authors: Tags: Research Source Type: research
Condition:   Lung Carcinoma Interventions:   Procedure: Participants smoke their usual brand of cigarettes for 26 weeks.;   Procedure: Participants will vape electronic cigarettes for 26 weeks.;   Drug: Nicotine Replacement;   Other: Questionnaire Administration Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
An experimental PET radiotracer is safe and appears effective for detectin...Read more on AuntMinnie.comRelated Reading: PET tracer proves effective for assessing immunotherapy Quitting smoking slows early lung cancer progression CT identifies candidates for sublobar resection for lung cancer CT radiomics predicts survival in NSCLC patients Falling lung cancer rates drive cancer decline in U.S.
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Condition:   Lung Carcinoma Interventions:   Procedure: Participants smoke their usual brand of cigarettes for 26 weeks.;   Procedure: Participants will vape electronic cigarettes for 26 weeks.;   Drug: Nicotine Replacement;   Other: Questionnaire Administration Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: Based on the findings of this study, the NK cell combination therapy may consider as a safe treatment method for stage IV NSCLC patients who had a history of failed platinum-based therapy without an increase in adverse events (AEs).PMID:34856706 | DOI:10.4143/crt.2021.986
Source: Cell Research - Category: Cytology Authors: Source Type: research
Am J Clin Oncol. 2021 Nov 30. doi: 10.1097/COC.0000000000000881. Online ahead of print.ABSTRACTOBJECTIVE: It is aimed to investigate the survival outcomes and prognostic factors after curative treatment of patients diagnosed with synchronous oligometastatic non-small cell lung carcinoma.MATERIALS AND METHODS: Fifty-two patients from 3 centers diagnosed between 2014 and 2019 were analyzed. The treatment results of thoracic and oligometastatic regions were retrospectively evaluated. The Kaplan-Meier method was used to determine the overall survival (OS) and progression-free survival (PFS) and log-rank tests for the factors a...
Source: Clinical Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: Our findings add some support for the role of menstrual and reproductive factors in lung carcinogenesis. However, these relationships were complex, and required further investigations addressing the biological mechanisms.PMID:34858781 | PMC:PMC8577983 | DOI:10.21037/tlcr-21-552
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research
Transl Lung Cancer Res. 2021 Oct;10(10):3875-3887. doi: 10.21037/tlcr-21-629.ABSTRACTBACKGROUND: Spontaneous ventilation video-assisted thoracoscopic surgery (SV-VATS) exhibits dual intraoperative and postoperative advantages for patients with non-small cell lung cancer (NSCLC). However, there is a lack of data regarding its long-term survival superiority over the double-lumen intubated mechanical ventilation video-assisted thoracoscopic surgery (MV-VATS) or thoracotomy.METHODS: A retrospective study was conducted from 2011 to 2018 in the First Affiliated Hospital of Guangzhou Medical University among patients with NSCLC w...
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research
In this study, the traditional boundary tracking algorithm was optimized, and the target neighborhood point boundary tracking method was proposed. The iterative method was used to binarize the lung MRI image, which was applied to the MRI images of 50 lung cancer patients in hospital. The patients were divided into two groups as the progression-free survival (PFS) and overall survival (OS) of surgical treatment group (experimental group, n = 25) and nonsurgical treatment group (control group, n = 25). The experimental group received surgical resection, while the control group received systemic chemotherapy. The results show...
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research
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