Seeing the forest through the trees: prioritising potentially functional interactions from Hi-C

Eukaryotic genomes are highly organised within the nucleus of a cell, allowing widely dispersed regulatory elements such as enhancers to interact with gene promoters through physical contacts in three-dimensio...

Source: Epigenetics and Chromatin - August 28, 2021 Category: Genetics & Stem Cells Authors: Ning Liu, Wai Yee Low, Hamid Alinejad-Rokny, Stephen Pederson, Timothy Sadlon, Simon Barry and James Breen Tags: Review Source Type: research