Ecthyma Gangrenosum in an Infant with Interleukin-1 Receptor-Associated Kinase 4 Deficiency

A 1-year-old boy was transferred to our hospital due to severe septic shock that led to cardiac arrest. The patient reportedly had fluid-refractory septic shock that required catecholamine administration. On admission, a characteristic skin rash covered the patient ’s entire body (Figure 1). His right buttock and thigh were reddish–purple and swollen (Figure 2). An incision was made in the right thigh, and the patient was diagnosed with necrotizing fasciitis. Surgical debridement was performed within the first 5 hours following his arrival.

Source: The Journal of Pediatrics - August 12, 2021 Category: Pediatrics Authors: Koji Kanno, Yoshiaki Cho, Shuichi Fujii, Yuki Ami, Osamu Nishizeki, Motoshi Sonoda, Masataka Ishimura, Naoki Fujiwara Tags: Rediscovering the Physical Exam Source Type: research