Research on antimicrobial residues activity in urine samples of hospitalized patients

Conclusion: Automated technique showed better performance when compared to manual technique, with sensitivity of 92.8% and 71.4%, respectively. The presence of antimicrobial residues may affect the recovery of bacteria in the urine, producing a false-negative result. Introdução: A infecção do trato urinário é bastante frequente em ambiente hospitalar, e a cultura de urina é padrão-ouro para o diagnóstico dessa doença, pois permite a identificação bacteriana e a realização do teste de suscetibilidade aos antimicrobianos. Amostras de urina de pacientes com forte suspeita de infecção que resultam em cultura negativa podem ocorrer devido à atividade de resíduos de antimicrobianos, os quais podem interferir no crescimento bacteriano in vitro e gerar resultados falso negativos. Objetivo: Verificar a ocorrência de culturas de urina falso negativas devido à presença de resíduos de antimicrobianos em amostras de pacientes internados no Hospital de Clínicas da Universidade Federal do Paraná. Material e métodos: Um total de 188 amostras de urina de pacientes internados foi selecionado aleatoriamente, durante o período de julho a dezembro de 2012. Todas as amostras foram avaliadas quanto ao resultado da cultura de urina, da bacteriúria e da pesquisa da atividade de resíduos de antimicrobianos por...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research

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This study investigated the feasibility of TVSE with RPS according to short-term outcomes and cosmesis.MethodsThis prospective multicenter study enrolled ten patients at three institutions. For the semi-quantification of each parameter, we administered questionnaires to assess pain (visual analogue scale), subjective/objective wound healing esthetics [photo series questionnaires (PSQ)], and quality of life (QOL).ResultsNo operative complications occurred, except one case of urinary tract infection, which was promptly cured with antibiotics. On day 0, pain was rated at 2.3  ± 0.67 at rest and 4.9&thinsp...
Source: Surgery Today - Category: Surgery Source Type: research
ConclusionsThe therapeutic effects of SVCP on treating UTIs might result from the up-regulation of innate immunity in the kidney. SVCP can be used as an alternative therapeutic agent for UTIs.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionsThe proposed framework of criteria may help clinical institutions to select the most suitable rule technology for the representation of CGs in general, and for the antibiotic prescription domain in particular, depicting the main aspects that lead to Computer Interpretable Guidelines (CIGs), such as Logic expressivity (Open/Closed World Assumption, Negation-As-Failure), Temporal Reasoning and Interoperability with existing HIS and clinical workflow. Future work will focus on providing clinicians with suggestions regarding new potential steps for CGs, considering process mining approaches and CGs Process Workflows...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
This study supports the potential of blue light for anti-infective and disinfection applications.
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
Publication date: Available online 16 January 2020Source: American Journal of Infection ControlAuthor(s): Bethany A. Wattengel, Sara DiTursi, Jennifer L. Schroeck, John A. Sellick, Kari A. MergenhagenBackgroundUrinary tract infections (UTIs) are common. Outpatient antimicrobial stewardship programs are emerging and a focused approach to UTIs is needed to help guide programs.MethodsData were collected by retrospective chart review of outpatients using encounters from January 2005 to March 2018. Antibiotic therapy was indicated if at least one UTI symptom was present. Antibiotic therapy was appropriate if consistent with gui...
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
ConclusionsEndoscopic treatment of symptomatic VUR in transplanted kidney is a safe and feasible procedure. The amount of bulking agent or duration between the transplantation and diagnosis of VUR does not have any impact on the success of the treatment. However, the younger age of the patients and the female gender seem to have a positive effect on the outcome of the procedure.
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research
AbstractBacterial urinary tract infections (UTIs) are one of the most common reasons for children to be admitted to hospital. Bacteria infect and invade the bladder (the lower urinary tract) and if the infection disseminates to the upper urinary tract, significant inflammation in the kidneys may arise. Inflammation is a double-edged sword: it is needed to clear bacteria, but if excessive, kidney tissue is injured. During injury, nephrons are destroyed and replaced with deposition of extracellular matrix and a renal scar. In this review, we explore the pathogenesis of UTIs and discuss the risk factors that result in dissemi...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsPediatric nephrologists have an important role in the diagnostic work-up and prevention of recurring nephrolithiasis.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
In this study, we aimed to identify the beta-lactam resistance phenotypes and genotypes of multidrug-resistant (MDR) non-repetitive GNP from 3 tertiary hospitals in Egypt. WZe studied 495 non-repetitive MDR Gram-negative isolates from patients with complicated intra-abdominal infections (cIAI), complicated urinary tract infection (cUTI), and lower respiratory tract infection (LRTI), collected as part of the “Study for Monitoring Antimicrobial Resistance Trends” (SMART) conducted in 3 tertiary hospitals in Cairo, Egypt, from 2015 to 2016. Identification and susceptibility testing of GNP to antimicrobials were te...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Conclusions: Independent of demographic variables, menopausal transition, postmenopause, and four menopausal symptoms (mood swing, depressive mood, palpitations, and urinary tract infection) increase the risk of depressive symptoms. PMID: 31951757 [PubMed - as supplied by publisher]
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
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