Relationship Between Macular Vessel Density and Total Retinal Blood Flow in Primary Open-angle Glaucoma

Precis: An association between macular vessel density (VD) and total retinal blood flow (TRBF) was demonstrated in subjects with primary open-angle glaucoma (POAG) and visual field (VF) loss. Purpose: The purpose of this study was to report relationships of macular VD metrics and TRBF in POAG. Materials and Methods: A total of 24 POAG and 19 healthy control subjects participated in the study. Subjects underwent optical coherence tomography and angiography for measurements of inner retinal thickness (IRT), VD, and spacing between large vessels (SLV) and small vessels (SSV). Doppler optical coherence tomography imaging was performed for TRBF measurement. In POAG subjects, automated perimetry was performed and VF loss expressed as mean deviation was measured. Results: Compared with the control group, POAG group had decreased VD, TRBF, IRT, and increased SLV (P
Source: Journal of Glaucoma - Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research