Stereotactic MR-guided online adaptive radiotherapy reirradiation (SMART reRT) for locally recurrent pancreatic adenocarcinoma: A case report

Introduction: Stereotactic MR-guided online adaptive radiation therapy (SMART) has demonstrated a superior radiotherapeutic ratio for pancreatic patients, by enabling dose escalation while minimizing the dose to the proximal gastrointestinal organs at risk through online adaptive radiotherapy. The safe delivery of stereotactic body radiation therapy (SBRT) is of particular importance in the reirradiation setting and has been historically limited to CT-based nonadaptive modalities. Herein, we report the first use of online adaptive radiotherapy in the reirradiation setting, specifically for treatment of locally recurrent pancreatic adenocarcinoma through SMART reirradiation (SMART reRT).

Source: Medical Dosimetry - June 10, 2021 Category: Radiology Authors: Delia G. Doty, Michael D. Chuong, Andres G. Gomez, John Bryant, Jessika Contreras, Tino Romaguera, Diane Alvarez, Rupesh Kotecha, Minesh P. Mehta, Alonso N. Gutierrez, Kathryn E. Mittauer Source Type: research