DrugNet: Network-based drug–disease prioritization by integrating heterogeneous data

Conclusions Our methodology suggests that new drugs can be repositioned by generating ranked lists of drugs based on a given disease query or vice versa. Our study shows that the simultaneous integration of information about diseases, drugs and targets can lead to a significant improvement in drug repositioning tasks. DrugNet is available as a web tool from http://genome2.ugr.es/drugnet/ (accessed 23.09.14). Matlab source code is also available on the website.
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research