Less airway inflammation and goblet cell metaplasia in an IL-33-induced asthma model of leptin-deficient obese mice
Obesity-associated asthma is a phenotype of severe asthma. Late-onset, non-eosinophilic and female-dominant phenotype is highly symptomatic and difficult to treat. Leptin, an adipokine, exerts an immunomodulat...
Source: Respiratory Research - Category: Respiratory Medicine Authors: Atsushi Kurokawa, Mitsuko Kondo, Ken Arimura, Shigeru Ashino and Etsuko Tagaya Tags: Research Source Type: research