An alginate-confined peroxygenase-CLEA for styrene epoxidation

Chem Commun (Camb). 2021 May 14. doi: 10.1039/d1cc01868j. Online ahead of print.ABSTRACTOxyfunctionalisation reactions in neat substrate still pose a challenge for biocatalysis. Here, we report an alginate-confined peroxygenase-CLEA to catalyse the enantioselective epoxidation of cis-β-methylstyrene in a solvent-free reaction system achieving turnover numbers of 96 000 for the biocatalyst and epoxide concentrations of 48 mM.PMID:33987632 | DOI:10.1039/d1cc01868j

Source: Chemical Communications - May 14, 2021 Category: Chemistry Authors: Friederike E H Nintzel Yinqi Wu Matteo Planchestainer Martin Held Miguel Alcalde Frank Hollmann Source Type: research