Mkx regulates the orthodontic tooth movement via osteoclast induction

ConclusionOrthodontic tooth movement experiments inMkx-deficient rats suggested thatMkx is involved in osteoclast induction at the alveolar bone surface on the compression side. This study reveals the possibility that Mkx plays a mechanosensory role in orthodontic tooth movement by inducing RANKL expression and osteoclastogenesis.

Source: Journal of Bone and Mineral Metabolism - May 14, 2021 Category: Orthopaedics Source Type: research