Flavor additives facilitate oral self-administration of nicotine solution in mice

ConclusionsFlavor additives increase nicotine oral consumption and help maintaining operant behavior in mice. Moreover, flavors can be very attractive and can have highreinforcing value by themselves. Thus, it is crucial that the investigation on how taste signals play an important role in modulating oral nicotine intake in rodent models remains explored.
Source: Psychopharmacology - Category: Psychiatry Source Type: research