Whole brain radiotherapy with hippocampal sparing using Varian HyperArc

The purpose of this work was to evaluate using Varian HyperArc as a planning and treatment solution for whole brain radiotherapy (WBRT) with hippocampal sparing following Radiation Therapy Oncology Group (RTOG) 0933 dosimetric criteria. Ten patients previously treated for intracranial lesions were retrospectively planned for WBRT with hippocampal sparing using HyperArc and a 2-arc coplanar VMAT technique. The whole brain and hippocampus were delineated on fused MRI and CT datasets. The planning target volume (PTV), defined as the whole brain excluding the hippocampal avoidance region, was prescribed 30 Gy in 10 fractions.

Source: Medical Dosimetry - March 23, 2021 Category: Radiology Authors: Cameron J. Sprowls, Amish P. Shah, Patrick Kelly, Doug R. Burch, Ryan S. Mathews, Cameron W. Swanick, Sanford L. Meeks Source Type: research