Abelson kinase ’s intrinsically disordered region plays essential roles in protein function and protein stability

The non-receptor tyrosine kinase Abelson (Abl) is a key player in oncogenesis, with kinase inhibitors serving as paradigms of targeted therapy. Abl also is a critical regulator of normal development, playing c...
Source: Cell Communication and Signaling - Category: Molecular Biology Authors: Tags: Research Source Type: research