Apolipoprotein C3 aggravates diabetic nephropathy in type 1 diabetes by activating the renal TLR2/NF- κB pathway

Apolipoprotein C3 (ApoC3) is a regulator of triglyceride metabolism and inflammation, and its plasma levels are positively correlated with the progression of diabetic nephropathy (DN) in patients. However, the role and underlying mechanism of ApoC3 in DN remain unclear.

Source: Metabolism - Clinical and Experimental - February 24, 2021 Category: Biomedical Science Authors: Huan Wang, Xiaomin Huang, Pengfei Xu, Xuejing Liu, Zihao Zhou, Fuhua Wang, Jingyi Li, Yuhui Wang, Xunde Xian, George Liu, Wei Huang Source Type: research