Molecules, Vol. 26, Pages 1196: Microwaves as “Co-Catalysts” or as Substitute for Catalysts in Organophosphorus Chemistry

Molecules, Vol. 26, Pages 1196: Microwaves as “Co-Catalysts” or as Substitute for Catalysts in Organophosphorus Chemistry
Molecules doi: 10.3390/molecules26041196
Authors:
Keglevich

The purpose of this review is to summarize the importance of microwave (MW) irradiation as a kind of catalyst in organophosphorus chemistry. Slow or reluctant reactions, such as the Diels-Alder cycloaddition or an inverse-Wittig type reaction, may be performed efficiently under MW irradiation. The direct esterification of phosphinic and phosphonic acids, which is practically impossible on conventional heating, may be realized under MW conditions. Ionic liquid additives may promote further esterifications. The opposite reaction, the hydrolysis of P-esters, has also relevance among the MW-assisted transformations. A typical case is when the catalysts are substituted by MWs, which is exemplified by the reduction of phosphine oxides, and by the Kabachnik–Fields condensation affording α-aminophosphonic derivatives. Finally, the Hirao P–C coupling reaction may serve as an example, when the catalyst may be simplified under MW conditions. All of the examples discussed fulfill the expectations of green chemistry.

Source: Molecules - February 23, 2021 Category: Chemistry Authors: Keglevich Tags: Review Source Type: research