An immunohistochemical study of potential diagnostic and therapeutic biomarkers of wild type gastrointestinal stromal tumours

ConclusionsAll five antibodies failed, individually or collectively, to represent highly sensitive and highly specific markers of wild type GIST. However, while HER2 has been excluded as a therapeutic biomarker, both EGFR and IGF1R are expressed by some wild type GISTs and are therefore potential therapeutic targets.This article is protected by copyright. All rights reserved.

Source: Histopathology - February 1, 2015 Category: Pathology Authors: Newton ACS Wong, Jenny Wingate, Elise Gradhand Tags: Original Article Source Type: research