SINE-B1 Distribution and Chromosome Rearrangements in the South American < b > < i > Proechimys < /i > < /b > gr. < b > < i > goeldii < /i > < /b > (Echimyidae, Rodentia)

Proechimys species are remarkable for their extensive chromosome rearrangements, representing a good model to understand genome evolution. Herein, we cytogenetically analyzed 3 different cytotypes ofProechimys gr.goeldii to assess their evolutionary relationship. We also mapped the transposable element SINE-B1 on the chromosomes ofP. gr.goeldii in order to investigate its distribution among individuals and evaluate its possible contribution to karyotype remodeling in this species. SINE-B1 showed a dispersed distribution along chromosome arms and was also detected at the pericentromeric regions of some chromosomes, including pair 1 and the sex chromosomes, which are involved in chromosome rearrangements. In addition, we describe a new cytotype forP. gr.goeldii, reinforcing the significant role of gross chromosomal rearrangements during the evolution of the genus. The results of FISH with SINE-B1 suggest that this issue should be more deeply investigated for a better understanding of its role in the mechanisms involved in the wide variety ofProechimys karyotypes.Cytogenet Genome Res

Source: Cytogenetic and Genome Research - February 8, 2021 Category: Genetics & Stem Cells Source Type: research