Does the Addition of Serum PAPP-A and β -hCG Improve the Predictive Value of Uterine Artery Pulsatility Index for Preeclampsia at 11–14 Weeks of Gestation? A Prospective Observational Study

ConclusionUtA-PI as a stand-alone test was found most useful for the prediction of PE. Addition of either or both of PAPP-A and fβ-hCG to UtA-PI did not improve the sensitivity of combined test with only a slight improvement in specificity and NPV. Their routine addition to UtA-PI studies is not recommended for prediction of PE at 11 –14 weeks of gestation in low- and lower-middle-income countries (LMIC).
Source: The Journal of Obstetrics and Gynecology of India - Category: OBGYN Source Type: research