Emerging therapies for endometriosis

Although endometriosis is one of the most common gynecologic diseases, treatment options have long been limited. Commonly used medications include nonsteroidal antiinflammatory drugs, progestins (including those in oral contraceptives), danazol, and GnRH agonists. Danazol and GnRH agonist use are associated with significant side-effects. Progestins use may also result in side-effects, including mood changes, breakthrough bleeding, breast tenderness, and bloating. Furthermore, progestins are not always effective; progestin resistance is common, occurring in 30% –50% of women using progestin-based therapies for endometriosis (1).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research