Two patients with chronic mucocutaneous candidiasis caused by TRAF3IP2 deficiency
We show that complete loss of TRAF3IP2 protein in humans does not impact B cell survival but manifests as an inborn error of IL-17 immunity leading to chronic mucocutaneous.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Samantha Shafer, Yikun Yao, William Comrie, Sarah Cook, Yu Zhang, G özde Yesil, Elif Karakoç-Aydiner, Safa Baris, Haluk Cokugras, Sezin Aydemir, Ayca Kiykim, Ahmet Ozen, Michael Lenardo Source Type: research
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