The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients

Mechanical ventilation can induce or even worsen lung injury, at least in part via overdistension caused by too large volumes or too high pressures. The complement system has been suggested to play a causative...

Source: Intensive Care Medicine Experimental - December 18, 2020 Category: Surgery Authors: Friso M. de Beer, Luuk Wieske, Gerard van Mierlo, Diana Wouters, Sacha Zeerleder, Lieuwe D. Bos, Nicole P. Juffermans, Marcus J. Schultz, Tom van der Poll, Wim K. Lagrand and Janneke Horn Tags: Research Source Type: research