Clinical Snippets

Pyoderma gangenosum (PG), an inflammatory neutrophilic dermatosis characterized by chronic ulcers, presents a diagnostic challenge owing to a lack of validated clinical criteria, laboratory tests, and histopathological markers. Three frameworks for diagnostic criteria (Su, PARACELSUS, and Delphi) have been described but remain unproven. In a single-site comparison of these diagnostic criteria in a PG cohort, Haag et  al. found that the PARACELSUS framework identified the highest proportion (89%) of patients with PG, whereas the Su and Delphi frameworks identified 74% of patients with PG.
Source: Journal of Investigative Dermatology - Category: Dermatology Tags: Clinical Snippets Source Type: research