Extracellular signal-regulated kinase 1/2 is required for complement component C1q and fibronectin dependent enhancement of Fc γ- receptor mediated phagocytosis in mouse and human cells

C1q is a soluble pattern recognition protein that regulates multiple leukocyte functions, and deficiency in C1q results in autoimmunity. C1q stimulates enhanced phagocytic function through multiple mechanisms ...
Source: BMC Immunology - Category: Allergy & Immunology Authors: Tags: Research Source Type: research