Evaluation of image quality with four positron emitters and three preclinical PET/CT systems

ConclusionsThe systems performed most optimal in terms of NEMA image quality parameters when using18F, where11C and89Zr performed slightly worse than18F. The performance was least optimal when using68Ga, due to large positron range. The large quantification differences prompt optimization not only by terms of image quality but also quantification. Further investigation should be performed to find an appropriate calibration and harmonization protocol and the evaluation should be conducted on a multi-scanner and multi-center level.

Source: EJNMMI Research - December 10, 2020 Category: Radiology Source Type: research