Influence of an Early Application of Mammalian Target of Rapamycin Inhibitors Everolimus and Sirolimus on Acute Vascular Inflammatory Responses After Ischemia-Reperfusion Injury.

CONCLUSIONS: Early use of mammalian target of rapamycin inhibitors may limit an inflammatory rise of interleukin 6 and vascular endothelial growth factor after ischemia-reperfusion injury and could be associated with a restriction in vascular cell transmigration.
PMID: 33272162 [PubMed - as supplied by publisher]

Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Wenzel M, Haffer H, Wang P, Richter M, Chun FKH, Kornberger A, Beiras-Fernandez A Tags: Exp Clin Transplant Source Type: research