The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex

The histone methyltransferase SETDB1 (also known as ESET) represses genes and various types of transposable elements, such as endogenous retroviruses (ERVs) and integrated exogenous retroviruses, through a dep...

Source: Epigenetics and Chromatin - November 30, 2020 Category: Genetics & Stem Cells Authors: Takeshi Tsusaka, Kei Fukuda, Chikako Shimura, Masaki Kato and Yoichi Shinkai Tags: Research Source Type: research