Gardnerella vaginalis promotes group B Streptococcus vaginal colonization, enabling ascending uteroplacental infection in pregnant mice

Group B Streptococcus (GBS) is a common vaginal bacterium and leading cause of invasive fetoplacental infections. GBS in the vagina can invade through the cervix to cause ascending uteroplacental infections or can be transmitted to the neonate during vaginal delivery. Some studies have found that women with a “dysbiotic” polymicrobial and/or Lactobacillus-depleted vaginal microbiota are more likely to harbor GBS. Gardnerella vaginalis is often the most abundant bacteria in the vaginas of women with dysbiosis, while being detected at lower levels in most other women, and has been linked with several a dverse pregnancy outcomes.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Original Research: Obstetrics Source Type: research