Characterization of an N-terminal Nav1.5 channel variant – a potential risk factor for arrhythmias and sudden death?

Alterations in the SCN5A gene encoding the cardiac sodium channel Nav1.5 have been linked to a number of arrhythmia syndromes and diseases including long-QT syndrome (LQTS), Brugada syndrome (BrS) and dilative ca...

Source: BMC Medical Genetics - November 19, 2020 Category: Genetics & Stem Cells Authors: Stefanie Scheiper-Welling, Paolo Zuccolini, Oliver Rauh, Britt-Maria Beckmann, Christof Geisen, Anna Moroni, Gerhard Thiel and Silke Kauferstein Tags: Research article Source Type: research