Arecoline enhances miR-21 to promote buccal mucosal fibroblasts activation.
CONCLUSION: MiR-21 overexpression in OSF may be due to the stimulation of areca nut, which was mediated by the TGF-β pathway. Our data suggested that the repression of miR-21 was a promising direction to palliate the development and progression of OSF.
PMID: 33191095 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - Category: General Medicine Authors: Yang HW, Yu CC, Hsieh PL, Liao YW, Chu PM, Yu CH, Fang CY Tags: J Formos Med Assoc Source Type: research